Generic Name: Dexamethasone phosphate
Dosage Form: Ampoules
Packaging: 2 mL x 3 Ampoules
*Packaging design and product name may be different in your country.
Each Ampoule of 2 ml contains :
Conditions where the anti-inflammatory and immunosuppressive effects of the corticosteroids are desirable, especially for intensive treatment during shorter periods.
Each milliliter contains Dexamethasone sodium phosphate equivalent to 4mg Dexamethasone phosphate.
(of hemorrhagic, traumatic, surgical or septic origin), the usual dose is 2 to 6 mg / kg body weight given as a single intravenous injection. This may be repeated in 2 to 6 hours, if shock persists. As an alternative, Dexonalin (Dexamethasone phosphate) injection 2 to 6 mg / kg body weight is given as a single intravenous injection followed immediately by the same dose in an intravenous infusion. Therapy with Dexamethasone phosphate injections are an adjunct to, and not a replacement for, conventional therapy.
Administration of high dose: of corticosteroid therapy should be continued only until the patient’s condition has stabilized and usually no longer than 48 to 72 hours.
Associated with primary or metastatic brain tumor, neurosurgery, head injury, pseudotumor cerebri or preoperative preparation of patients with increased intracranial pressure secondary to brain tumor: Initially 10mg (2.5ml) of Dexonalin injection intravenously followed by 4mg (1mL) every 6 hours by I.M. injection until the symptoms of cerebral edema subside. Response is usually noted within 12 to 24 hours: dosage may be reduced after 2 to 4 days and gradually discontinued over a period of 5 to 7 days.
High doses of Dexonalin injection are recommended for initiating short-term intensive therapy for acute life-threatening cerebral edema.
Following the high loading dose schedule of the first day of therapy. The dose is scaled down over the 7 – 10 days period of intensive therapy and subsequently reduced to zero over the next 7 – 10 days. When maintenance therapy is required, this should be changed to oral Dexamethasone as soon as possible.
Doses should then be tapered to zero over the ensuring 7 days.
In acute self-limited allergic disorders of acute exacerbations of chronic allergic disorders (e.g., acute allergic rhinitis, acute attacks of seasonal allergic bronchial asthma, urticaria medicamentosus, and contact dermatoses).
Generally are employed when affected joints or areas are limited to one or two sites.
Some of usual single doses are:
|Site of Injection||Volume of Injection (ml)||Amount of Dexamethasone Phosphate (mg)|
|– Large joints (e.g., Knee)||0.5 to 1||2 to 4|
|– Small joints (e.g., Interphalangeal, Temporomandibular)||0.2 to 0.25||0.8 to 1|
|– Bursae||0.5 to 0.75||2 to 3|
|– Tendon sheaths||0.1 to 0.25||0.4 to 1|
|– Soft-tissue infiltration||0.5 to 1.5||2 to 6|
|– Ganglia||0.25 to 0.5||1 to 2|
The frequency of injection varies from once every 3 to 5 days to once every 2 to 3 weeks, depending on the response to treatment.
*The information provided above is general in nature and for informational purposes only. It is NOT a substitute for the advice of your doctor. You must always consult your healthcare professional before starting any medication/supplementation program.